Experience the many health and wellness benefits of our high dose IV vitamin C drip therapy tailored to your individual needs.
Vitamin C drips are a form of intravenous (IV) therapy that involves administering this vitamin directly into the bloodstream through a vein. This method allows for rapid and efficient absorption of vitamin C, bypassing the digestive system and enabling the body to receive a greater concentration of the essential nutrient than would be possible through oral supplements or diet alone.
Vitamin C drips are used for various purposes, including boosting immune system function, improving overall wellness, and aiding in the treatment of certain acute and chronic health conditions. Some potential benefits of vitamin C drips include increased energy levels, reduced inflammation, faster healing and recovery, and enhanced detoxification.
Increasing research is starting to show the myriad of anticancer properties, such as targeting vulnerabilities many cancer cells share, such as redox imbalance, epigenetic reprogramming and oxygen-sensing regulation.
A vast number of studies have shown encouraging anti-cancer activity of vitamin C at high doses in various cancer types . The most investigated have been leukaemia [20–24], colon cancer [13–20], melanoma [21–25], pancreatic cancer [2, 19, 26] and prostate cancer [27–29].
Similar results have been described for the treatment of non-small-cell lung cancer (NSCLC) , breast cancer [29, 30], ovarian cancer [29, 31, 32], hepatocellular carcinoma [33, 34], malignant mesothelioma [35, 36], thyroid cancer [37, 38], oral squamous cell carcinoma , neuroblastoma  and glioma, including the difficult-to-treat glioblastoma multiform (GBM) [4, 41, 42].
One notable example of the progress in vitamin C pre-clinical research is the recent work in hard-to-treat Kirsten Rat Sarcoma Viral Oncogene Homolog (KRAS) driven tumours, such as KRAS mutant colorectal cancer (CRC) [13, 15, 20].
Based on prior studies by Yun et al.  and Aguilera et al. , Cenigaonan- dia-Campillo et al.  used elevated doses of vitamin C (5–10mM) in KRAS mutant CRC tumours, both in vitro and in vivo. They showed that Vitamin C was able to target common metabolic aberrancies by decreasing adenosine triphosphate (ATP) and glucose transporter 1 (GLUT-1) levels, as well as by dissipating the mito- chondrial membrane potential, which could sensitize KRAS mutant CRC cells to current treatments such as chemotherapy.
In the majority of cancer types, most of the in vivo studies have shown inhibition of tumour growth (40–60%) by using elevated doses of ascorbate (1-4g/ kg) either intravenously (IV) or intraperitoneally (IP) [13, 43–45]
According to research a fully competent immune system is required to maximize the antiproliferative effect of vitamin C in breast, colorectal, melanoma, and pancreatic tumors.
High-dose Vitamin C modulates infiltration of the tumor microenvironment by cells of the immune system and delays cancer growth in a T cell-dependent manner.
Vitamin C not only enhances the cytotoxic activity of adoptively transferred CD8 T cells but also cooperates with immune checkpoint therapy (ICT) in several cancer types. Combination of this vitamin and ICT can be curative in models of mismatch repair-deficient tumors with high mutational burden.
More literature  states that mounting evidence indicates that Vitamin C has the potential to be a potent anti-cancer agent when administered intravenously and in high doses (high-dose IVC).
Early phase clinical trials have confirmed safety and indicated efficacy of IVC in eradicating tumour cells of various cancer types. In recent years, the multi-targeting effects of vitamin C were unravelled, demonstrating a role as cancer-specific, pro-oxidative cytotoxic agent, anti-cancer epigenetic regulator and immune modulator, reversing epithelial-to-mesenchymal transition, inhibiting hypoxia and oncogenic kinase signalling and boosting immune response.
Moreover, high-dose IVC is powerful as an adjuvant treatment for cancer, acting synergistically with many standard (chemo-) therapies, as well as a method for mitigating the toxic side-effects of chemotherapy.
In more scientific terms, research has shown that due to vitamin C complex pharmacokinetics, only intravenous administration allows reaching sufficiently high plasma concentrations required for most of the antitumor effects observed in preclinical studies (>0.250 mM). Moreover, vitamin C entry into cells is tightly regulated by SVCT and GLUT transporters, and is cell type-dependent.
Importantly, besides its well-recognized pro-oxidant effects, vitamin C modulates TET enzymes promoting DNA demethylation and acts as cofactor of HIF hydroxylases, whose activity is required for HIF-1α proteasomal degradation. Furthermore, at pharmacological concentrations lower than those required for its pro-oxidant activity (<1 mM), vitamin C in specific genetic contexts may alter the DNA damage response by increasing 5-hydroxymethylcytosine levels.
These more recently described vitamin C mechanisms offer new treatment opportunities for tumors with specific molecular defects (e.g., HIF-1α over-expression or TET2, IDH1/2, and WT1 alterations). Moreover, vitamin C action at DNA levels may provide the rationale basis for combination therapies with PARP inhibitors and hypomethylating agents.
In palliative care, high-dose VitC is currently gaining ground due to its highly safe and tolerable profile. Not only is high-dose vitamin C known to relieve pain in cancer patients , vast clinical evidence suggests that it has a significant positive impact on patients’ well-being [1, 2-5, 7-10]. This might be due to the frequent hypovitaminosis and vitamin C deficiency in cancer patients [6, 11, 12], which are commonly enhanced by anti-neo- plastic treatments .
For instance, a retrospective, multicentre, epidemiological cohort study  showed amelioration of appetite, fatigue, depression and sleep disorders in breast cancer and terminal cancer patients suffering from a wide variety of cancer types that received complementary 7.5g IVC while being treated by respective standard regimens.
More recently, a single-center, parallel-group, single-blind interventional study also in breast cancer patients  showed a similar and significant reduction of symptoms such as nausea, fatigue, tumor pain and loss of appetite by administering 25g of IVC per week in addition to their current standard treatment. Favourably, no new side effects were reported after initiation of IVC treatment.
Moreover, another retrospective study showed that patients with radiotherapy-resistant bone metastasis did not only have less pain and better performance measures when given high-dose VitC, they had a median survival time of 10 months as compared to the 2 months median survival time within the control group .
Overall, high dose VitC administered as a single agent has not only been shown to be safe and well-tolerated in cancer patients, but also to ameliorate pain and to improve quality of life in the palliative care setting.
The administration of a high dose Vitamin C IV drip involves a few key steps to ensure patient safety, comfort, and effectiveness of the treatment.
Intro-call: After you have contacted us, a specialised team member will call you and advice about the next steps depending on each individual case. Our consultant specialised in complementary care will also speak with you personally to design your tailored treatment plan.
Preparation: A customized blend of vitamins, minerals, and amino acids, including the high dose of Vitamin C, is prepared in a sterile environment. This mixture is then added to a saline solution in an IV bag, which will be used to deliver the nutrients directly into your bloodstream.
IV Insertion: A healthcare professional will locate a suitable vein, typically in the arm or hand, and cleanse the area with an antiseptic solution. A small needle, called a cannula, is then inserted into the vein. The cannula is connected to a thin plastic tube, which is attached to the IV bag containing the nutrient solution.
Infusion: Once the IV is securely in place, the high dose Vitamin C solution begins to drip slowly into your bloodstream. The rate of infusion is carefully monitored and adjusted as needed by the healthcare professional. The entire process typically takes between 1 to 3 hours, depending on the dosage and individual factors.
Monitoring: Throughout the treatment, the healthcare professional will monitor your vital signs and overall well-being to ensure a safe and comfortable experience. They may also adjust the drip rate or make other modifications to the treatment as necessary.
Post-Treatment: After the infusion is complete, the cannula is gently removed, and a bandage is applied to the injection site. You may be asked to stay for a brief observation period to ensure there are no adverse reactions. Once you're cleared, you can resume your normal activities.
It is essential to receive high dose Vitamin C IV drips from a reputable and licensed healthcare provider to ensure proper administration, safety, and effectiveness.
Remember to follow any post-treatment recommendations provided by your healthcare professional to maximize the benefits of the treatment.
References for IVC monotherapy in palliative care and quality of life (EOL)